A study now suggests that in West Africa tests to identify Mtbc in culture miss a substantial fraction of cases, with dire consequences for the patients and for TB control efforts.
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A new report on burnout syndrome in critical care health care professionals gives key stakeholders guidance on mitigating the development of burnout syndrome and calls for initiating research to examine ways to prevent as well as treat burnout syndrome.
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In the study, researchers worked with a species of Old World monkeys, rhesus macaques to reproduce the trial results of RV144, the only HIV vaccine that has been tested and shown to reduce the rate of HIV acquisition in a phase III clinical trial.
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A special form of RNA called extra-coding RNA, or ecRNA, controls the careful targeting to add or remove methyl groups to chromosomal DNA of the adult neuron. The ecRNAs are fundamental regulators of DNA methylation patterns in the adult brain through interaction with DNA methyltransferase enzymes, are involved in creation of memories, and the ecRNAs may offer a promising future therapeutic avenue to treat neuropsychiatric disease.
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Biologists have found a unique version of a filament-forming protein in human cells that insects lack. Providing structural support and protection against such conditions as blistering, cataracts and dementia, intermediate filament proteins (IFs) reside in every cell in the human body.
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Hallmarks of early brain overgrowth have been discovered in cells of people with autism. These findings suggest that it is possible to use stem cell reprogramming technologies developed in the past decade to model the earliest stages of complex disorders and to evaluate potential therapeutic drugs.
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In a look-back study of medical records, researchers concluded that a major operation to fuse the spines of children with a rare form of severe, early-onset scoliosis can be eliminated in many cases.
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